All Therapeutic Areas

Therapeutic Area

Respiratory & Rare Disease

6 intermediates

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Area Overview

Respiratory & Rare Disease Portfolio

The portfolio connects respiratory programs represented by cystic-fibrosis and leukotriene-pathway therapies with selected rare-disease programs present in the product catalog.

Classification is based on terminal APIs in the product catalog; product counts update with the catalog.

Representative Terminal APIs

Elexacaftor (VX-445) Montelukast Sapropterin

6 catalog intermediates

Intermediates for this Area

E-19

(S)-2,2,4-trimethylpyrrolidinehydrochloride

(S)-2,2,4-三甲基吡咯烷盐酸盐

Application

Elexacaftor (VX-445)

CAS No. 1897428-40-8

C₇H₁₆ClN

E-20

1,3-Dimethyl-1H-pyrazole-4-sulfonamide

1,3-二甲基-1H-吡唑-4-磺胺

Application

Elexacaftor (VX-445)

CAS No. 88398-53-2

C₅H₉N₃O₂S

E-21

3-(3,3,3-Trifluoro-2,2-dimethylpropoxy)-1H-pyrazole

3-(3,3,3-三氟-2,2-二甲基丙氧基)-1H吡唑

Application

Elexacaftor (VX-445)

CAS No. 2229861-15-6

C₈H₁₁F₃N₂O

E-43

5-Deoxy-L-arabinose phenylhydrazone

5-脱氧-L-阿拉伯糖苯基腙

Application

Sapropterin

CAS No. 59245-36-2

C₁₁H₁₆N₂O₃

H-07

2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol

2-(2-(3-(2-(7-氯-2-喹啉基)乙烯基)苯基)-3-羟基丙基)苯基-2-丙醇

Application

Montelukast

CAS No. 142569-70-8

C₂₉H₂₈ClNO₂

H-08

2-[1-(Mercaptomethyl)cyclopropyl]acetic acid

2-[1-(巯基甲基)环丙基]乙酸

Application

Montelukast

CAS No. 162515-68-6

C₆H₁₀O₂S

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